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Signaling biopolymer
- Generates an ordered, biomimetic signal pattern.
- The neural-network-inspired architecture allows complex, coordinated signals to be generated precisely.
No release of chemical substances
We have mastered cell communication and signaling.
Accell1 is a signaling platform built on biopolymers with a neural-network-inspired architecture. We do not deliver chemistry — we deliver a “signal instruction” that mimics the natural communication between cells, with no release of chemical substances.
Mechanism
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Coordinated biomimetic signals
- Coordinated signal packages mimic the natural rhythms and dynamics of proliferative communication.
- What is transmitted is the signal pattern itself, with no chemical intermediary.
The biopolymer acts as an active communicator, not a reagent
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Recognised as authentic communication
- The signal acts as a “key” matching the way the cell recognises natural proliferative communication.
- The cell receives it as an authentic biological signal.
The lock-and-key fit ensures high specificity and authenticity of the signal
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Synergistic activation of multiple pathways
- Several signaling pathways are triggered at once.
- Synergy and crosstalk amplify the cell's final response.
Declared performance increase of 400–500%
Research
Studies confirming and validating the use of the technology were carried out at the following institutions.
Source: Bioprocess Optimisation Technology (BOT) — documentation, PDF01
Bacterial cultures
- 5-fold greater Escherichia coli colony growth
- 4–5-fold greater E. coli colony growth in a second, independent validation
- 5-fold faster Salmonella detection — 5 hours instead of the standard 24
University of Rzeszów · JSH Hamilton network laboratory, Łódź · 2021
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Stem cells
- 12-fold more cells in colonies compared with the control
- The first passage produced whole cultures of healthy cells instead of single-cell multiplication
- No signs of ageing even at the 7th passage
Polish Academy of Sciences, Warsaw · 2021
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Fungal cultures
- 16-fold greater Lentinula edodes growth measured as dry mass
- Morphological change towards a significantly more cohesive structure
- Significantly greater mass gain in Armillaria mellea
Medical University of Warsaw · 2022
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Industrial applications
- 60% greater daily algae growth in industrial cultivation
Industrial Algae Farm, Malaysia · 2021
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Environmental protection
- Foaming reduced from 30% to 13% in biological wastewater treatment
BioTreaT GmbH in cooperation with the University of Innsbruck · 2022
Pathways activated through biomimetic signal induction
Microorganisms
- Signal reception by natural receptors
- Activation of the culture's biological response
- Amplification of natural signaling
Eukaryotic cells
- Recognition of authentic proliferative communication
- Simultaneous activation of multiple pathways
- Crosstalk within the cell signaling network
Crops
- Mechanosensory pathways
- Gravitropic systems
- Mechanosensitive ion channels
- Ca2+ pathways
- Root sensory systems
- Abiotic stress MAPK cascades
A platform technology for signaling
A new layer of interaction
- Signal instead of chemistry
- No chemical substances released into the process
- The layer of interaction shifts from chemical to signal-based
Synergy of multiple pathways
- Crosstalk within the signaling network
- Simultaneous activation of multiple pathways
- Declared performance increase of 400–500%
Universality
- Microorganisms
- Eukaryotic cells
- Crops
A scalable tool
- The biopolymer is selected automatically for the process parameters
- A molecular machine working inside the process
- From laboratory to production scale
Coordinated signals
- Biopolymers with a neural-network-inspired architecture
- Generation of biomimetic signals
Lock-and-key fit
- High signal specificity
- Authenticity of recognition
Declared performance increase
300 – 0%
Achieved through the simultaneous activation of multiple signaling pathways in response to a recognised biomimetic signal.
Activation of multiple pathways
- Synergistic activation at once
- Crosstalk within the cell signaling network
An amplified effect
- Compared with uncoordinated signals
- Compared with single growth factors